CCL17 blockade as a therapy for osteoarthritis pain and disease
نویسندگان
چکیده
منابع مشابه
CCL17 blockade as a therapy for osteoarthritis pain and disease
BACKGROUND Granulocyte macrophage-colony stimulating factor (GM-CSF) has been implicated in the pathogenesis of a number of inflammatory diseases and in osteoarthritis (OA). We identified previously a new GM-CSF→Jmjd3→interferon regulatory factor 4 (IRF4)→chemokine (c-c motif) ligand 17 (CCL17) pathway, which is important for the development of inflammatory arthritis pain and disease. Tumour ne...
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چکیده ندارد.
15 صفحه اولMetabolic Syndrome as a Risk Factor for Osteoarthritis
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BACKGROUND Osteoarthritis is the leading musculoskeletal cause of disability in western society. General practitioners are central in the management of patients with osteoarthritis. OBJECTIVE To review the literature on factors associated with pain in osteoarthritis and discuss the implications of these findings for management. DISCUSSION It is well known that there is a modest correlation ...
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ژورنال
عنوان ژورنال: Osteoarthritis and Cartilage
سال: 2020
ISSN: 1063-4584
DOI: 10.1016/j.joca.2020.02.214